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If you’re reading this, chances are you’ve heard of, and already know plenty about, THC and CBD...but what about cannabigerol (CBG)? Daenerys Targaryen may be the Mother of Dragons, but CBG is the Mother of Cannabinoids. Consider CBG the true O.G. of hemp and cannabis, because she came first. Don’t get it twisted. (More on that in a few paragraphs…)
CBG is being studied for a variety of potential therapeutic benefits and uses including: pain relief and anti-inflammatory properties, slowing the proliferation of cancer cells, antidepressant and antibacterial properties, and more.
Over the past few months, our President, Colin, and our Leadership Team have been hard at work trying and testing out new products to enhance your health and wellness routine. We’re excited to bring you Energy Enhanced our Peppermint Essence Tincture. The powerful duo of CBG and CBD boosts energy and focus, and we’ve infused MCT oil and B12 to pack even more of a powerful punch.
And now, onto today’s lesson: all things CBG. Let’s get started, shall we?
CBG is one of more than 100 cannabinoids derived from hemp and cannabis. Similar to CBD, it’s considered non-psychoactive, meaning it won’t give you the sensation of feeling high. Now let’s take a moment to rewind to Israel in 1964…
Before their research and names were as well-known and widely-accepted as they are today, cannabis researchers Raphael Mechoulam and Yehiel Gaoni discovered cannabigerol (CBG), a non-psychoactive cannabinoid that showed great promise in treating a wide variety of symptoms and conditions.
Wait a second…if CBG was discovered more than 50 years ago, why is this the first time you’re hearing about it? Excellent question. Keep reading…
While hemp and cannabis plants grow, they produce cannabigerolic acid (CBGA), the first cannabinoid that forms within the plant. Researchers and canna-experts consider CBG as the precursor to THC, CBD and CBC. (The “stem cell” cannabinoid is another nickname associated with this “new-to-you”compound.) CBG must be extracted from the plant in the earliest stages of growth in order to get the goods; if it’s not extracted at just the right time, CBG will have already been converted into a different compound, like the CBD we all know and love.
Also good to know: CBG is present in less than 1% of hemp and cannabis strains, compared to around 20% for CBD. To extract comparable amounts of CBG, it takes a lot (seriously, a lot) more plant material, making a lot more work for harvesters - a true labor of love.
The brief window of opportunity before CBG birthes other cannabinoids and the abundance of plant material it takes to extract sufficient amounts of this powerful cannabinoid make it one of the most expensive hemp- or cannabis-derived compounds to produce. At the risk of confusing you, here’s another name drop for CBG: the Rolls Royce of Cannabinoids. The good stuff, the pot of gold at the end of the rainbow.
Think of CBG as the opposite of Arya Stark, a girl has no name, because CBG has *all of the* names.
CBG and other cannabinoids work with a network of receptors in your body known as the endocannabinoid system (ECS), similar to the nervous and lymphatic systems. The ECS spans through your entire body, and regulates a wide array of bodily functions including: mood, metabolism, immune response, appetite regulation, sleep patterns and more. Researchers largely believe the primary function of the ECS is to support homeostasis (balance) in the body.
While our bodies produce molecules called endocannabinoids, hemp produces phytocannabinoids (this includes CBG); phytocannabinoids simply imitate endocannabinoids to work naturally with our ECS.
There are three primary components of the ECS:
- Cannabinoid receptors - CBG interacts with both CB1 and CB2 receptors
- Endocannabinoids - CBG may boost anandamide, a naturally-occurring endocannabinoid
- Metabolic enzymes - CBG is believed to mitigate the psychoactive effects of THC
While CBG has shown to react with both receptors, it primarily interacts with CB2. Think of this as a lock and key system, with receptors as locks and cannabinoids as keys. Make sense?
CB1 and CB2 receptors regulate neurohormones which actively affect physiological processes including: mood, pain appetite and pain response. When cannabinoids like CBG interact with these receptors, a response is activated and physiological changes occur (think relief from pain and inflammation or an uplifted mood).
Why integrate CBG into your daily wellness routine? Let’s let science do the talking here. Decades of research illustrates CBG’s potential health benefits. Here are just a few of them:
CBG may have powerful anti-inflammatory properties. According to research, CBG may benefit those suffering from inflammatory conditions like IBD (inflammatory bowel disease). One study looked at the effect CBG has on IBD was performed on mice subjects. After being induced with colitis, the mice subjects were then given CBG, which effectively relieved inflammation.  This demonstrates that CBG has the potential to ease inflammation in humans.
CBG may act as an antioxidant and protect the nervous system from damage. A study  conducted by researchers in Italy illustrates the efficacy of CBG due to its neuroprotective effects. Upon completion of the study, researchers shared: “...we encourage the use of CBG against neurodegeneration and in those pathological conditions where neuroinflammation and oxidative stress play a main role.”
According to researchers, CBG is an active antibacterial agent, especially when it comes to bacterial strains such as MRSA resistant to common antibiotics.  Studies show CBG’s ability to manage “gram-positive bacteria”, a specific class of mycobacteria, fungi and bacteria. This same research suggests CBG is much more effective than CBD or THC in fighting these bacterial strains.
When it comes to treating symptoms and specific conditions, current research indicates CBG’s tremendous potential as one of the most potent, therapeutically diverse cannabinoids that hemp and cannabis have to offer.
CBG for Depression
Scientists believe CBG boosts anandamide, the endocannabinoid known best for increasing dopamine levels and regulating both appetite and sleep.  To those who know her best, anandamide has been nicknamed the “bliss” molecule. Simply put, more anandamide likely equates to enhanced mood. A lack of anandamide is often associated with a wide array of conditions, including depression and schizophrenia, whereas balanced levels of Miss Bliss come with feelings of joy, contentment and well-being.
CBG for Anxiety
Other research illustrates CBG may inhibit the brain’s uptake of gamma-aminobutyric (GABA). Sidebar: GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. Blocking the brain’s absorption of this amino acid leads to increased extracellular concentrations of GABA, which is beneficial in the treatment of not only anxiety, but insomnia, certain types of chronic pain and muscle tremors. Which leads us to our next topic...
CBG for Pain
According to a 2010 review in the British Journal of Pharmacology, Dr. Ethan B Russo shares his findings on the potential of CBG’s pain-relieving properties. This is true for other cannabinoids including CBD and THC, but there is mounting evidence that CBG may have even more pain-relieving properties than THC.
Other current and rapidly evolving research on CBG shows its potential in treating numerous other conditions, including: Inflammatory Bowl Disease (IBD), Osteoporosis, Glaucoma, Colon Cancer, Huntington’s Disease, MRSA, Overactive Bladder, Psoriasis and Eczema.
Well, we’d like to formally introduce you to something near and dear to our hearts (and endocannabinoid systems) - meet Energy Enhanced.
Our Energy Enhanced Peppermint Essence Tincture is the natural pick-me-up you've been searching for. CBG and Broad Spectrum CBD come together in a big way to help you find your sweet spot, AKA homeostasis, and truly SOAR.
This Peppermint Essence Tincture brings together the goodness of hemp, MCT oil and B vitamins to lift your mood, enhance your energy and improve your focus. From personal experience, yes, it really is as good as it sounds. Scout’s honor - I made it to Brownie status.
Easy-to-dose, I take 1 to 2 dropper fulls in the morning before I brew a cup of mushroom coffee. I’m actively trying to cut caffeine as a daily habit, and with Energy Enhanced it’s a whole lot easier than I thought it would be. I’ve gone from 1-2 cups of java a day, to a few per week. Boom.
While we are just at the beginning of understanding the full potential of this powerful compound, cannabigerol, the research and anecdotal evidence are promising. Known by many names, CBG is perhaps most well-known as both the Mother and Rolls Royce of Cannabinoids. Basically, she’s kind of a big deal. Long story short: CBG is the precursor to the cannabinoids we already know and love (think THC, CBD, etc.) and must be harvested at just the right time to reap the benefits of this special compound. On top of that, it’s a minor cannabinoid, meaning it’s only present in about 1% of cannabis and hemp plants.
Scientists and canna-experts express excitement over CBG’s potential as one of the most therapeutically diverse cannabis- or hemp-derived compounds. It’s being studied and used for its antibacterial, anti-inflammatory and neuroprotective properties. Researchers are beginning to better understand its promise for treating conditions like anxiety, depression, pain and more.
CBG’s difficulty to extract and rarity, combined with its vast and plentiful potential therapeutic benefits make CBG the most sought-after wellness component of hemp currently on the market. Interested in seeing what it’s all about? We’ve got you. In our Energy Enhanced Peppermint Essence Tincture, we’ve harnessed the best of the hemp plant, CBG and CBD, and added MCT oil and B12 to enhance your energy and increase your focus.*
SOAR Director of Content Marketing